Publication in Nature Research
The framework of this research allows tissue cell type composition to emerge as a potential marker measuring homeostasis that can be utilized in prospective studies in regenerative medicine.
MaCSBio reports a novel methodology to quantify the tissue cell type composition in adipose tissue that can be used both in future studies as well as in existing datasets employing gene expression quantification with our established signature matrix. In generalized terms, this framework allows tissue cell type composition to emerge as a potential marker measuring homeostasis that can be utilized in prospective studies in regenerative medicine.
The overview of studies presented in comparison with our findings, reflect the state of the adipose tissue field from the lens of tissue cell type composition. Finally, reported novel cell type-specific markers have great potential in identifying difficult cell types (such as adipose tissue macrophages and eosinophils) and are promising candidates to be evaluated in future studies working with adipose tissue samples.
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