Projects

The FHML department of Toxicogenomics participates in the following international and innovative research projects. Here we provide insights into what topics our research projects are tackling and who the actors involved in them are.

  • BReIN - Brightlands e-Infrastructure for Neurohealth
  • CEFIC LRI C4 – Towards the development of an omics data analysis framework (ODAF) for regulatory application
  • Children with Cancer 
  • CIN - Brain miRNA’s as markers of drug induced changes in neural integrity - Testing mechanistic and placebo-controlled studies in which we will administer a psychedelic drug (i.e. psilocybin) that is known to affect neural integrity - 
  • Enhanced cross-omics visualizations in toxicogenomics
  • EU FP7 - TransQST - Translational quantitative systems toxicology to improve the understanding of the safety of medicines - 
  • EU H2020 - EUToxRisk - Animal-free hazard and risk assessment of chemicals
  • EU H2020 - OpenRiskNet Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment 
  • GYM project
  • H2020 SCREENED aims to develop three-dimensional (3D) cell-based in vitro tests to better characterize the effects of endocrine disruptors on thyroid gland function. 
  • Immunotoxicity of biotargeted nanomedicines Methods and criteria for evaluating potential immunotoxicity of biotargeted nanomedicines 
  • INTERREG VLA-NED Herinneringen Towards an earlier diagnosis of Alzheimers Disease (AD)
  • MiFood - Personalized Nutrition Evaluation of personalized preventive strategies based on synergistic effects between vioactive compounds present in fruits and vegetables 
  • NWO Complexity "Complex Systems Framework for Non-alcoholic fatty liver disease (NAFLD) 
  • ONTOX

  • SafetyNet

  • TiO2 

  • APAP induced liver injury (DILI) finalized Drug Induced Liver Injuries: Studying the underlying mechanisms
  • BaP finalized - BaP-induced hepatocarcinogenesis
  • BE BASIC finalized - Biobased solutions for a sustainable society —
  • CEFIC DECO finalized - Data-integration for Endpoints, Chemoinformatics and Omics 
  • Collaboration UM and LCSB finalized -  Analysis of Environmental-Genome Interactions in the development of neurodegenerative diseases 
  • EU FP7 - Detective finalized -  Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems
  • EU FP7 - diXa finalized - Data Infrastructure for Chemical Safety
  • EU FP7 - EnviroGenomarkers finalized - Genomics biomarkers of environmental health
  • EU FP7 - Exposomics finalized 
  • EU FP7 - HeCaToS finalized - Hepatic and Cardiac Toxicity Systems modelling 
  • EU FP7 - iCORDI finalized - International Collaboration on Research Data Infrastructure
  • EU FP7 - PHYTOME finalized - Phytochemicals to reduce nitrite in meat products 
  • Hepatocarcinogenesis finalized - Gene expression profiling of oxidative genotoxic compounds in hepatocarcinogenesis
  • MeDIP seq finalized - Methylated DNA Immunoprecipitation Sequencing 
  • miRNAno finalized - Toxicogenomic studies on engineered carbon nanomaterials
  • NGI - Netherlands Toxicogenomics Centre (NTC) finalized - An applied system biology approach to predict chemical safety 
  • ZonMW - ASAT2 finalized - Systems toxicology supported data infrastructure for human risk assessment