Fluid balance important for survival of kidney patients
Measuring the amount of fluid in the body of a kidney patient treated with dialysis on a weekly basis appears to be more important than previously thought. Too much or too little bodily fluid increases the risk of death in these patients. This is the conclusion of Marijke Dekker’s doctoral research, carried out at the Catharina Hospital in Eindhoven and the Maastricht University Medical Centre. Dekker defended her PhD at Maastricht University on 17 September.
Dekker conducted a large-scale data analysis involving data from haemodialysis patients treated all over the world. She showed that it is important to measure the fluid balance in haemodialysis patients on a regular basis. This allows nephrologists, haemodialysis nurses and dietitians to better tailor the treatment to each individual patient’s needs, such as preventing malnutrition, measuring inflammation and striving for the optimal blood pressure.
On the basis of this research, Dekker and her supervisors contributed to the drafting of international recommendations for the optimal treatment of blood pressure and fluid balance in haemodialysis patients. This innovative method is now standard care in the Catharina Hospital, Elkerliek Hospital and Maastricht UMC+.
What is haemodialysis?
Worldwide, more than two million patients with poor kidney function have to go to hospital several times a week to have waste products and excess fluid removed by means of an artificial kidney.
MONDO Initiative
The nephrology department at the Catharina Hospital and the Deurne Dialysis Centre at the Elkerliek Hospital together form one of the largest haemodialysis centres in the Netherlands. To assess the quality of the treatment and ultimately improve patient outcomes, the Catharina Hospital has long participated, alongside the Maastricht UMC+, in an international consortium known as the MONDO Initiative (MONitoring Dialysis Outcomes). This partnership was created in order to collect data from large groups of haemodialysis patients worldwide, enabling researchers to identify which factors are harmful for different groups of patients.
Marijke Dekker defended her PhD dissertation "Associations and dynamics of risk factors in hemodialysis patients" at Maastricht University on Thursday 17 September. Her supervisor was internist-nephrologist Prof. Jeroen Kooman of the Maastricht UMC+. Co-supervisors were Prof. Peter Kotanko of the Renal Research Institute New York and internist-nephrologist Dr Stijn Konings of the Catharina Hospital.
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