L.C. Hewitt
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Liu, D. H. W., Kim, Y.-W., Sefcovicova, N., Laye, J. P., Hewitt, L. C., Irvine, A. F., Vromen, V., Janssen, Y., Davarzani, N., Fazzi, G. E., Jolani, S., Melotte, V., Magee, D. R., Kook, M.-C., Kim, H., Langer, R., Cheong, J.-H., & Grabsch, H. I. (2023). Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial. British Journal of Cancer, 128(12), 2318-2325. https://doi.org/10.1038/s41416-023-02257-3More information about this publication
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Silva, A. N. S., Saito, Y., Yoshikawa, T., Oshima, T., Hayden, J. D., Oosting, J., Earle, S., Hewitt, L. C., Slaney, H. L., Wright, A., Inam, I., Langley, R. E., Allum, W. H., Nankivell, M. G., Hutchins, G., Cunningham, D., & Grabsch, H. I. (2022). Author response to: Increasing frequency of gene copy number aberrations is associated with immunosuppression and predicts poor prognosis in gastric adenocarcinoma. British Journal of Surgery, 109(9), E106. https://doi.org/10.1093/bjs/znac160More information about this publication
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Silva, A. N. S., Saito, Y., Yoshikawa, T., Oshima, T., Hayden, J. D., Oosting, J., Earle, S., Hewitt, L. C., Slaney, H. L., Wright, A., Inam, I., Langley, R. E., Allum, W., Nankivell, M. G., Hutchins, G., Cunningham, D., & Grabsch, H. I. (2022). Increasing frequency of gene copy number aberrations is associated with immunosuppression and predicts poor prognosis in gastric adenocarcinoma. British Journal of Surgery, 109(3), 291-297. https://doi.org/10.1093/bjs/znab460More information about this publication
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Sundar, R., Liu, D. H. W., Hutchins, G. G. A., Slaney, H. L., Silva, A. N. S., Oosting, J., Hayden, J. D., Hewitt, L. C., Ng, C. C. Y., Mangalvedhekar, A., Ng, S. B., Tan, I. B. H., Tan, P., & Grabsch, H. I. (2021). Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination. Gut, 70(10), 1823-1832. https://doi.org/10.1136/gutjnl-2020-320805More information about this publication
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Challoner, B. R., von Loga, K., Woolston, A., Griffiths, B., Sivamanoharan, N., Semiannikova, M., Newey, A., Barber, L. J., Mansfield, D., Hewitt, L. C., Saito, Y., Davarzani, N., Starling, N., Melcher, A., Grabsch, H. I., & Gerlinger, M. (2021). Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes. Journal of the National Cancer Institute, 113(1), 88-98. https://doi.org/10.1093/jnci/djaa051More information about this publication
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Meier, A., Nekolla, K., Hewitt, L. C., Earle, S., Yoshikawa, T., Oshima, T., Miyagi, Y., Huss, R., Schmidt, G., & Grabsch, H. (2020). Hypothesis-free deep survival learning applied to the tumour microenvironment in gastric cancer. Journal of Pathology, 6(4), 273-282. https://doi.org/10.1002/cjp2.170More information about this publication
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Kerckhoffs, K. G. P., Liu, D. H. W., Saragoni, L., van der Post, R. S., Langer, R., Bencivenga, M., Iglesias, M., Gallo, G., Hewitt, L. C., Fazzi, G. E., Vos, A. M., Renaud, F., Yoshikawa, T., Oshima, T., Tomezzoli, A., de Manzoni, G., Arai, T., Kushima, R., Carneiro, F., & Grabsch, H. (2020). Mucin expression in gastric- and gastro-oesophageal signet-ring cell cancer: results from a comprehensive literature review and a large cohort study of Caucasian and Asian gastric cancer. Gastric Cancer, 23(5), 765-779. https://doi.org/10.1007/s10120-020-01086-0More information about this publication
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Davarzani, N., Hewitt, L. C., Hale, M. D., Melotte, V., Nankivell, M., Hutchins, G. G. A., Cunningham, D., Allum, W. H., Langley, R. E., Jolani, S., & Grabsch, H. I. (2020). Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial. Diseases of the Esophagus, 33(8), Article doaa058. https://doi.org/10.1093/dote/doaa058More information about this publication
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Sundar, R., Ng, A., Zouridis, H., Padmanabhan, N., Sheng, T., Zhang, S., Lee, M. H., Ooi, W. F., Qamra, A., Inam, I., Hewitt, L. C., So, J. B.-Y., Koh, V., Nankivell, M. G., Langley, R. E., Allum, W. H., Cunningham, D., Rozen, S. G., Yong, W. P., ... Tan, P. (2019). DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial. European Journal of Cancer, 123, 48-57. https://doi.org/10.1016/j.ejca.2019.09.016More information about this publication
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Hewitt, L. C., Saito, Y., Wang, T., Matsuda, Y., Oosting, J., Silva, A. N. S., Slaney, H. L., Melotte, V., Hutchins, G., Tan, P., Yoshikawa, T., Arai, T., & Grabsch, H. I. (2019). Correction to: KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study. Gastric Cancer, 22(6), 1204-1205. https://doi.org/10.1007/s10120-019-00975-3More information about this publication
L.C. Hewitt
Project Leader
Precision Medicine
GROW, School for Oncology & Reproduction
Fac. Health, Medicine and Life Sciences