Dr J. Hoeks
Wefers, J., van Moorsel, D., Hansen, J., Connell, N. J., Havekes, B., Hoeks, J., van Marken Lichtenbelt, W. D., Duez, H., Phielix, E., Kalsbeek, A., Boekschoten, M. V., Hooiveld, G. J., Hesselink, M. K. C., Kersten, S., Staels, B., Scheer, F. A. J. L., & Schrauwen, P. (2018). Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America, 115(30), 7789-7794. https://doi.org/10.1073/pnas.1722295115
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Dahlmans, D., Houzelle, A., Andreux, P., Jorgensen, J. A., Wang, X., de Windt, L. J., Schrauwen, P., Auwerx, J., & Hoeks, J. (2017). An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism. Molecular Metabolism, 6(11), 1429-1442. https://doi.org/10.1016/j.molmet.2017.08.007
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van Moorsel, D., Hansen, J., Havekes, B., Scheer, F. A. J. L., Jorgensen, J. A., Hoeks, J., Schrauwen-Hinderling, V. B., Duez, H., Lefebvre, P., Schaper, N. C., Hesselink, M. K. C., Staels, B., & Schrauwen, P. (2016). Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity. Molecular Metabolism, 5(8), 635-645. https://doi.org/10.1016/j.molmet.2016.06.012
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Dahlmans, D., Houzelle, A., Schrauwen, P., & Hoeks, J. (2016). Mitochondrial dynamics, quality control and miRNA regulation in skeletal muscle: implications for obesity and related metabolic disease. Clinical Science, 130(11), 843-852. https://doi.org/10.1042/CS20150780
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Hanssen, M. J., Hoeks, J., Brans, B., van der Lans, A. A., Schaart, G., van den Driessche, J. J., Jorgensen, J. A., Boekschoten, M. V., Hesselink, M. K., Havekes, B., Kersten, S., Mottaghy, F. M., van Marken Lichtenbelt, W. D., & Schrauwen, P. (2015). Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nature Medicine, 21(8), 863-865. https://doi.org/10.1038/nm.3891
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van der Lans, A. A., Hoeks, J., Brans, B., Vijgen, G. H. E. J., Visser, M. G., Vosselman, M. J., Hansen, J., Jorgensen, J. A., Wu, J., Mottaghy, F. M., Schrauwen, P., & van Marken Lichtenbelt, W. D. (2013). Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. Journal of Clinical Investigation, 123(8), 3395-3403. https://doi.org/10.1172/JCI68993
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Wu, J., Bostrom, P., Sparks, L. M., Ye, L., Choi, J. H., Giang, A. H., Khandekar, M., Virtanen, K. A., Nuutila, P., Schaart, G., Huang, K., Tu, H., van Marken Lichtenbelt, W. D., Hoeks, J., Enerback, S., Schrauwen, P., & Spiegelman, B. M. (2012). Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell, 150(2), 366-376. https://doi.org/10.1016/j.cell.2012.05.016
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Hoeks, J., & Schrauwen, P. (2012). Muscle mitochondria and insulin resistance: a human perspective. Trends in Endocrinology and Metabolism, 23(9), 444-450. https://doi.org/10.1016/j.tem.2012.05.007
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Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., Kornips, C. F. P., Hesselink, M. K. C., Kunz, I., Schrauwen-Hinderling, V., Blaak, E. E., Auwerx, J., & Schrauwen, P. (2011). Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metabolism, 14(5), 612-22. https://doi.org/10.1016/j.cmet.2011.10.002
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Nabben, M., Shabalina, I. G., Kornips, C. F. P., Van Beurden, D., Cannon, B., Schrauwen, P., Nedergaard, J., & Hoeks, J. (2011). Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. Biochimica et Biophysica Acta-bioenergetics, 1807(9), 1095-1105. https://doi.org/10.1016/j.bbabio.2011.04.003
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Publications
Dr J. Hoeks
Associate Professor of Human Biology
Department of Nutrition and Movement Sciences
NUTRIM School of Nutrition and Translational Research in Metabolism
Faculty of Health, Medicine and Life Sciences