Key words: interventional oncology; intra-arterial therapy; percutaneous ablation; liver metastatic breast cancer; renal cell carcinoma

"Interventional oncology in the management of breast and kidney cancer"

Interventional oncology (IO) uses image guided procedures as local treatment in cancer patients. During the past decade IO has gained prominence as a minimally-invasive cancer treatment option besides surgery, external beam radiation and systemic therapy. In this thesis, we investigate different IO procedures in liver metastatic breast cancer patients (part I) and patients with renal cell carcinoma (part II). We aim to identify factors associated with safety, efficacy and overall survival to improve treatment stratification in daily clinical practice and for development of further studies.