Bachelor Student Prize Winner

Eighteen students completed their bachelor's degree in 2020 with a thesis that was labelled ‘excellent’ by their faculty. Here you will find a short introduction to these excellent theses in the form of an "elevator pitch" from each student, plus a video in which the supervisor briefly addresses the lucky winner.

Ruben Tammaro

  Faculty of Science and Engineering | Maastricht Science Programme

"In Silico Tomography of Membrane-Embedded Mycobacterial Type VII Secretion Systems"

Ruben's elevator pitch 
In my thesis I have developed an automated pipeline for the generation of simulated electron microscopy data of the ESX-1 protein complex, involved in the infection by Mycobacterium Tuberculosis. The pipeline can now be employed to generate training datasets for artificial intelligence algorithms, which would then be used to detect and identify ESX-1 in real experimental data, which would lead to the determination of its three-dimensional structure, a task that so far has not been accomplished. Knowing the structure of ESX-1 will allow for the development of novel strategies to combat and prevent tuberculosis worldwide.