Publications
Stratakis N, Gielen M, Margetaki K, de Groot RHM, Apostolaki M, Chalkiadaki G, Vafeiadi M, Leventakou V, Godschalk RW, Kogevinas M, Stephanou EG, Zeegers MP, Chatzi L. PUFA status at birth and allergy-related phenotypes in childhood: a pooled analysis of the Maastricht Essential Fatty Acid Birth (MEFAB) and RHEA birth cohorts. Br J Nutr. 2018 Jan;119(2):202-210. doi: 10.1017/S0007114517003348.
Stratakis N, Gielen M, Margetaki K, de Groot RHM, Apostolaki M, Chalkiadaki , Vafeiadi M4, Leventakou V, Karachaliou M, Godschalk RW, Kogevinas M, Stephanou EG, Zeegers MP, Chatzi L. Polyunsaturated fatty acid status at birth, childhood growth, and cardiometabolic risk: a pooled analysis of the MEFAB and RHEA cohorts. Eur J Clin Nutr. 2018 May 16. doi: 10.1038/s41430-018-0175-1. [Epub ahead of print]
Brouwer-Brolsma EM, van de Rest O, Godschalk R, Zeegers MPA, Gielen M, de Groot RHM. Associations between maternal long-chain polyunsaturated fatty acid concentrations and child cognition at 7 years of age: The MEFAB birth cohort. Prostaglandins Leukot Essent Fatty Acids. 2017 Nov;126:92-97. doi: 10.1016/j.plefa.2017.09.012. Epub 2017 Sep 22.
Stratakis N, Gielen M, Margetaki K, Godschalk RW, van der Wurff I, Rouschop S, Ibrahim A, Antoniou E, Chatzi L, de Groot RHM, Zeegers MP. Polyunsaturated fatty acid levels at birth and child-to-adult growth: Results from the MEFAB cohort. Prostaglandins Leukot Essent Fatty Acids. 2017 Nov;126:72-78. doi: 10.1016/j.plefa.2017.09.004. Epub 2017 Sep 9.
van der Wurff ISM, Bakker EC, Hornstra G, Kirschner PA, Gielen M, Godschalk RWL, Kremers S, Zeegers MP, de Groot RHM. Association between prenatal and current exposure to selected LCPUFAs and school performance at age 7. Prostaglandins Leukot Essent Fatty Acids. 2016; 108:22-29.
Jochems SH, Gielen M, Rump P, Hornstra G, Zeegers MP. Potential programming of selected cardiometabolic risk factors at childhood by maternal polyunsaturated fatty acid availability in the MEFAB cohort. Prostaglandins Leukot Essent Fatty Acids.2015 Jun 14. doi: 10.1016/j.plefa.2015.06.001. [Epub ahead of print].
van der Wurff ISM, de Groot RHM, Stratakis N, Gielen M, Hornstra G, Zeegers M. Maastricht essential fatty acid birth cohort. Lipid Technology 2015; 27(3): 59-62.
de Vries PS, Gielen M, Rizopoulos D, Rump P, Godschalk R, Hornstra G, Zeegers MP. Association between polyunsaturated fatty acid concentrations in maternal plasma phospholipids during pregnancy and offspring adiposity at age 7: the MEFAB cohort. Prostaglandins Leukot Essent Fatty Acids 2014; 91:81-85.
Stratakis N, Gielen M, Chatzi L, Zeegers MP. Effect of maternal n-3 long-chain polyunsaturated fatty acid supplementation during pregnancy and/or lactation on adiposity in childhood: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Nutr 2014; 68:1277-87. Epub 2014 Aug 13.
Dirix CE, Hogervorst JG, Rump P, Hendriks JJ, Bruins M, Hornstra G. Atopic manifestations during childhood and fetal exposure to arachidonic acid. Clin Exp Allergy 2011; 41:1493-1494.
Veldwijk J, Scholtens S, Hornstra G, Bemelmans WJ. Body mass index and cognitive ability of young children. Obes Facts 2011; 4:264-9. Epub 2011 Aug 13.
Dirix CE, Hornstra G, Nijhuis JG. Fetal learning and memory: weak associations with the early essential polyunsaturated fatty acid status. Prostaglandins Leukot Essent Fatty Acids 2009; 80:207-12.
Dirix CE, Kester AD, Hornstra G. Associations between term birth dimensions and prenatal exposure to essential and trans fatty acids. Early Hum Dev 2009; 85 525-30.
Dirix CE, Kester AD, Hornstra G. Associations between neonatal birth dimensions and maternal essential and trans fatty acid contents during pregnancy and at delivery. Br J Nutr 2009; 101:399-407.
Dirix CE, Hogervorst JG, Rump P, Hendriks JJ, Bruins M, Hornstra G. Prenatal arachidonic acid exposure and selected immune-related variables in childhood. Br J Nutr 2009; 102:387-397.
Bakker EC, Hornstra G, Blanco CE, Vles JS. Relationship between long-chain polyunsaturated fatty acids at birth and motor function at 7 years of age. Eur J Clin Nutr 2009; 63:499-504.
Rutters F, Nieuwenhuizen AG, Vogels N, Bouwman F, Mariman E, Westerterp-Plantenga MS. Leptin-adiposity relationship changes, plus behavioral and parental factors, are involved in the development of body weight in a Dutch children cohort. Physiol Behav 2008; 93:967-74.
Slinger JD, van Breda E, Keizer H, Rump P, Hornstra G, Kuipers H. Insulin resistance, physical fitness, body composition and leptin concentration in 7-8 year-old children. J Sci Med Sport 2008; 11: 132-8.
Krabbendam L, Bakker E, Hornstra G, van Os J. Relationship between DHA status at birth and child problem behaviour at 7 years of age. Prostaglandins Leukot Essent Fatty Acids 2007; 76: 29-34.
Vogels N, Westerterp KR, Posthumus DL, Rutters F, Westerterp-Plantenga MS. Daily physical activity counts vs structured activity counts in lean and overweight Dutch children. Physiol Behav 2007; 92:611-6.
Hornstra G, van Eijsden M, Dirix C, Bonsel G. Trans fatty acids and birth outcome: some first results of the MEFAB and ABCD cohorts. Atheroscler Suppl 2006; 7:21-3.
Vogels N, Posthumus DL, Mariman EC, Bouwman F, Kester AD, Rump P, Hornstra G, Westerterp-Plantenga MS. Determinants of overweight in a cohort of Dutch children. Am J Clin Nutr 2006; 84:717-24.
Hornstra G. Essential fatty acids during pregnancy. Impact on mother and child. In: Hornstra G, Uauy R, Yang X (eds): The impact of maternal nutrition on the offspring. Nestlé Nutrition Workshop Series Pediatric program, vol 55, pp 83-100, Nestec Ltd, Vevey/S. Karger AG, Basel, 2005.
Vlaardingerbroek H, Hornstra G. Essential fatty acids in erythrocyte phospholipids during pregnancy and at delivery in mothers and their neonates: comparison with plasma phospholipids. Prostaglandins Leukot Essent Fatty Acids 2004; 71:363–74.
Hornstra G, De Vriese SR. Essential fatty acid metabolism during pregnancy and early human development. In: G. van der Vusse (Ed): Advances in Molecular and Cell Biology, volume 33: Lipobiology, Chapter 24, pp. 503-29 (2004).
Otto SJ, de Groot RHM, Hornstra G. Increased risk of postpartum depressive symptoms is associated with slower normalization after pregnancy of the functional docosahexaenoic acid status. Prost Leukotr Ess Fatty Acids 2003; 69:237-43.
Bakker EC, Ghys AJ, Kester AD, Vles JS, Dubas JS, Blanco CE, Hornstra G. Long-chain polyunsaturated fatty acids at birth and cognitive function at 7 y of age. Eur J Clin Nutr 2003; 57: 89-95.
Rump P, Hornstra G. The n-3 and n-6 polyunsaturated fatty acid compositions of plasma phospholipids in pregnant women and their infants. Relation with maternal linoleic acid intake. Clin Chem Lab Med 2002; 40:32-39.
Ghys A, Bakker E, Hornstra G, Van den Hout M. Red blood cell and plasma phospholipid arachidonic and docosahexaenoic acid levels at birth and cognitive development at 4 years of age. Early Human Dev 2002; 69: 83-90.
Rump P, Verstappen F, Gerver WJ, Hornstra G. Body composition and cardiorespiratory fitness indicators in prepubescent boys and girls. Int J Sports Med. 2002;23: 50-54.
Rump P, Mensink RP, Hornstra G. Interaction between a common variant of the cholesteryl ester transfer protein gene and the apolipoprotein E polymorphism: effects on plasma lipids and lipoproteins in a cohort of 7-year-old- children. Nutr Metabol Cardiovasc Dis 2002; 12: 317-24.
Rump P, Popp-Snijders C., Heine RJ, Hornstra G. Components of the insulin resistance syndrome in 7-year-old children: relations with birth weight and the polyunsaturated fatty acid content of umbilical cord plasma phospholipids. Diabetologia 2002; 45: 349-55.
Rump P, Otto SJ, Hornstra G. Leptin and phospholipid-esterified docosaheaxenoic acid concentrations in plasma of women: observations during pregnancy and lactation. Eur J Clin Nutr 2001; 55:244-51.
Rump P, Otto SJ, Hornstra G. Leptin and phospholipid-esterified docosaheaxenoic acid concentrations in plasma of women: observations during pregnancy and lactation. Eur J Clin Nutr 2001; 55:244-51.
Otto SJ, Houwelingen AC van, Badart-Smook A, Hornstra G. Comparison of the peripartum and postpartum phospholipid polyunsaturated fatty acid profiles of lactating and nonlactating women. Am J Clin Nutr 2001; 73:1074-79.
Otto SJ, Badart-Smook A, Houwelingen ACvan, Hornstra G. Changes in the maternal essential fatty acid profile during early pregnancy and the relation of the profile to diet. Am J Clin Nutr 2001; 73:302-07.
Rump P, Mensink RP, Kester ADM, Hornstra G. Essential fatty acid composition of plasma phospholipids and weight at birth: A study in term neonates. Am J Clin Nutr 2001; 73:797-806.
Hornstra G. Importance of polyunsaturated fatty acids of the n-6 and n-3 families for early human development. Eur J Lipid Sci Technol 2001;103:379-89.
Hornstra G. Essential fatty acids in mothers and their neonates. Am J Clin Nutr 2000;71:1262S-69S.
Otto SJ, Houwelingen ACv, López-Jaramillo P, Hornstra G. Effects of pregnancy-induced hypertension on the essential fatty acid statuses of Ecuadorian and Dutch women. Am J Obstet and Gynecol 1999; 180:1185-90.
Zeijdner EE, Houwelingen AC van, Kester ADM, Hornstra G. The essential fatty acid status in plasma pospholipids of mother and neonate after multiple pregnancy. Prost Leukotr Essent Fatty Acids 1997; 56:395-401.
Al MDM, Houwelingen AC van, Hornstra G. Relation between birth order and the maternal and neonatal docosahexaenoic acid status. Eur J Clin Nutr 1997; 51:548-53.
Badart-Smook A, Houwelingen ACv, Al MDM, Kester ADM, Hornstra G. Fetal growth is associated positively with maternal intake of riboflavin and negatively with maternal intake of linoleic acid. J Amer Diet Ass 1997; 97:867-70.
Otto SJ, Houwelingen AC van, Antal M, Manninen A, Godfrey K, López-Jaramillo P, Hornstra G. Maternal and neonatal essential fatty acid status in phospholipids: an international comparative study. Eur J Clin Nutr 1997; 51: 232-42.
Houwelingen AC van, Foreman-van Drongelen MMHP, Nicolini U, Nicolaides KH, Al MDM, Kester ADM, Hornstra G. Essential fatty acid status of fetal phospholipids: similar to postnatal values obtained at comparable gestational ages. Early Hum Dev 1996; 46:141-52.
Al MDM, Badart-Smook A, Houwelingen ACvan, Hasaart THM, Hornstra G. Fat intake of women during normal pregnancy: Relationship with maternal and neonatal essential fatty acid status. J Am Coll Nutr 1996; 15:49-55.
Foreman-van Drongelen MMHP, Zeijdner EE, Houwelingen AC van, Kester ADM, Al MDM, Hasaart THM, Hornstra G. Essential fatty acid status measured in umbilical vessel walls of infants born after a multiple pregnancy. Early Hum Dev 1996; 46:205-15.
Hornstra G, Houwelingen AC v. Essential fatty acids, pregnancy and pregnancy outcome. In: K. Berger (Ed):Lipids and Nutrition: current hot topics. PJ Barnes & Associates, Bridgewater 1996; 57-69.
Hornstra G, Al MDM, Houwelingen AC van, Foreman-van Drongelen HHMP. Essential fatty acids, pregnancy and pregnancy outcome. In: Bindels JG, Goedhart AC, Visser HKA (Eds): Recent developments in infant nutrition. Kluwer Academic Publishers, Dordrecht, Boston, London, 1996, 51-63.
Al MDM, Houwelingen AC van, Kester ADM, Hasaart THM, Jong EP de, Hornstra G. Maternal essential fatty acid patterns during normal pregnancy and their relationship to the neonatal essential fatty acid status. Br J Nutr 1995; 74:55-68.
Postle AD, Al MDM, Burdge GC, Hornstra G. The composition of individual molecular species of plasma phosphatidylcholine in human pregnancy. Early Hum Dev 1995; 43:47-58.
Al MD, van Houwelingen AC, Badart-Smook A, Hasaart TH, Roumen FJ, Hornstra G. The essential fatty acid status of mother and child in pregnancy-induced hypertension: a prospective longitudinal study. Am J Obstet Gynecol 1995; 172:1605-14.
Al MDM, Houwelingen AC van, Badart-Smook A, Hornstra G. Some aspects of neonatal essential fatty acid status are altered by linoleic acid supplementation of women during pregnancy. J Nutr 1995; 125:2822-30.
Foreman-van Drongelen MMHP, Al MDM, Houwelingen AC van, Blanco CE, Hornstra G. Comparison between the essential fatty acid status of preterm and full-term infants, measured in umbilical vessel walls. Early Hum Dev 1995; 42: 241-51.
Hornstra G, Al MDM, Houwelingen AC van, Foreman-van Drongelen MMHP. Essential fatty acids in pregnancy and early human development. Eur J Obstet Gynecol 1995; 61: 57-62.
Houwelingen AC van, Hornstra G. Trans fatty acids in early human development. In: C. Galli, AP. Simopoulos AP, E. Tremoli (Eds): Fatty acids and lipids: Biological aspects. World Rev Nutr Diet, Karger, Basel 1994; 75: 175-8.
Houwelingen AC van, Puls J, Hornstra G. Essential fatty acid status during early development. Early Hum Dev 1992; 31: 97-111.
Hornstra G, Al MDM, Gerrard JM, Simonis MMG. Essential fatty acid status of neonates born to inuit mothers: comparison with caucasian neonates and effect of diet. Prostaglandins Leukot Essent Fatty Acids 1992; 45: 125-30.
Hornstra G. Essential fatty acids, pregnancy and pregnancy complications: a roundtable discussion. In: A. Sinclair and R. Gibson (Eds): Essential fatty acids and eicosanoids. American Oil Chemist's Society. Campaign, Illinois 1992; 177-82.
Schouw YT van der, Al MDM, Hornstra G, Bulstra-Ramakers MTEW, Huisjes HJ. Fatty acid composition of serum lipids of mothers and their babies after normal and hypertensive pregnancies. Prostaglandins Leukot Essent Fatty Acids 1991; 44: 247-52.
Al MDM, Hornstra G, van der Schouw YT, Bulstra-Ramakers MTEW, Huisjes HJ. Biochemical EFA status of mothers and their neonates after normal pregnancy. Early Hum Dev 1990; 24: 239-48.
Hornstra G, Houwelingen AC van, Simonis M, Gerrard JM. Fatty acid composition of umbilical arteries and veins: possible implications for the fetal EFA status. Lipids 1989; 24: 511-7.