MaCSBio was founded in April 2015 by senior researchers at FHS, FHML and FPN as a unique axis for top research in systems biology and mathematical modelling in Limburg. Professor Ilja Arts is a project leader for one of the first MaCSBio projects and accepted the role of scientific director with enthusiasm.

MaCSBio, which aims to promote scientific development with the support of the province, employs more than twenty-five researchers from various disciplines, such as mathematics, physics, neuroscience and biology. They work in transdisciplinary teams to create new models that further our understanding of living systems and develop new strategies for healthier living. MaCSBio was officially opened on 17 May during the first Science Day. The research lines presented by Ilja Arts build on the start-up projects that prompted the centre's foundation in 2015.

Systems biology is the future of life sciences. With an increasing amount of data being generated using the latest techniques, such as genomics and imaging, it has become possible to develop computational and mathematical models that foster our understanding of complex human biology.