11
Jul
16:30
- 19:30
Maastricht Systems Biology Forum
Classification methods
This edition of the Forum is focussed on classification methods applicable to problems in physiology and biology. The aim is to provide new points of contact and stimulate discussion amongst diverse groups of researchers who are currently developing and/or applying classification approaches in physiology, or who are interested in doing so in the near future.
This working group brings together researchers in the Maastricht area who are interested in the development and application of “systems biology”. The main aim is to share research, experience and, through this exchange, inspire and initiate new research directions and collaborations. The meeting takes place roughly every three months in the Brains Unlimited building.
Programme
| Time | Subject |
|---|---|
| 16:30 | Classification: From Traditional Techniques to Recent Advances Pietro Bonizzi (DKE) In statistics and machine learning, classification is the task of identifying to which of a set of categories a new observation belongs. This talk will map out the techniques that are currently available providing a brief overview of their advantages and limitations and highlighting the applicability of newer advances in the field |
| 17:10 | From gene expression to patient phenotype: towards a new classification of atrial fibrillation Stef Zeemering (CARIM) The CATCH-ME consortium aims to develop a new classification of atrial fibrillation (AF), by identifying the driving molecular AF mechanisms based on AF patient phenotype. For this purpose a large multi-center tissue bank has been established, and RNA-seq data of atrial tissue samples and detailed clinical characteristics of patients with and without AF have been acquired. This talk will focus on various strategies to explain observed differences in gene expression profiles by means of patient phenotype. |
| 17:50 | Tissue Cell Type Heterogeneity in health and disease Gökhan Ertaylan (MaCSBio) Tissue homeostasis is maintained at the cellular level, such that tissues are composed of diverse types of cells interacting to perform tasks necessary for the functioning of the organism. Understanding this tissue specific cellular heterogeneity and homeostasis, is essential for developing regenerative therapies for targeted tissues and also to comprehend the development of various diseases within the tissue. In this presentation we will introduce our framework on identifying tissue-specific cell types, their respective ratio within the tissue sample and associated markers for each cell type based on their transcriptomics profiles within adipose tissue. |
| 18:30 | Networking over drinks/snacks |
| 19:30 | End |
